Hospital acquired Pneumonia
Conditions
Interventions
prior atorvastatin treatment group:prior atorvastatin treatment
compare group:none
Sponsors
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients were eligible for enrolment if they were diagnosed with acute ischemic stroke by magnetic resonance imaging (MRI); aged between 18 and 80 years; Glasgow Coma Scale (GCS) = 8;
Exclusion criteria
Exclusion criteria: Patients were excluded from the study if they were moribund or not expected to survive 28 days because of an underlying irreversible medical condition; had active pneumonia when admitted to ICU or had extrapulmonary infection during ICU stay; had a known intolerance to statins or were unable to have enteral administration of statin; had severe liver disease (acute liver failure or chronic liver disease with Child-Pugh classification C); had a serum alanine aminotransferase (ALT) or aspartate aminotransferase (AST) level greater than three times the normal value or a serum creatinine kinase (CK) level greater than five times the upper limit of normal levels; had commenced statin therapy less than 4 weeks before hospital admission or had statin stopped for more than 72 hours before the development of ischemic stroke; were pregnant or if informed consent could not be obtained.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of HAP;incidence of VAP; | — |
Countries
China
Contacts
Public ContactYu Yuetian
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Outcome results
None listed