Ischemic stroke
Conditions
Interventions
Aspirin group:Aspirin, 100mg, qd
Clopidogrel Group:Clopidogrel 75mg, qd
Aspirin+Clopidogrel Group:Aspirin, 100mg, qd+Clopidogrel,75mg, qd
Warfarin Group:Warfarin, INR 2-2.5
Pradaxa Group:Pradaxa 150mg, bid
Sponsors
Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 year old patients with acute ischemic stroke; 2. onset within 72 hours, cerebral infarction confirmed by head MR and CT scan, without cerebral hemorrhage or micro hemorrhage; 3. signed informed consent and able to cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1. history of intracranial hemorrhage or subarachnoid hemorrhage; 2. with hemorrhagic transformation after cerebral infarction this time; 3. the survival of patients was less than 1 year; 4. with contraindications to antithrombotic therapy, or allergy to related drugs; 5. serious heart, liver or renal insufficiency patients; 6. with severe pulmonary or systemic infection; 7. with other brain organic diseases, such as brain tumors, cerebral aneurysm, intracranial vascular malformations, et al; 8. participated in other clinical researches within 3 months; 9. HIV positive, syphilis antibody positive, hepatitis B or hepatitis C patients; 10. with severe mental disorders, cognitive dysfunction, or cant understand and sign the informed consent; 11. with coagulation dysfunction, active or tendency to bleeding; 12. with high blood pressure difficult to control, severe diabetes or other diseases affect the function of the limb.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS;mRS;ADL;HRQoL;MOCA;CDT; | — |
Countries
China
Contacts
Public ContactYUN XU
Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing
Outcome results
None listed