Breast Cancer
Conditions
Interventions
1: CTC detection and BRCA1 gene expression detection
Sponsors
Guizhou Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. CTCs test results were positive in 18-75 years old patients with pathologically confirmed breast cancer; 2. Peripheral blood was collected at the time of acquisition; 3. CTC was isolated from peripheral blood of patients, and the expression of CTCs and BRCA1 were analyzed; 4. Data analysis for all patients, to understand the correlation between CTCs count, typing and BRCA1 gene expression and the baseline characteristics of patients, and to understand the correlation between BRCA1 gene expression and the efficacy of platinum in CTCs.
Exclusion criteria
Exclusion criteria: 1. CTC test results negative patients; 2. Patients without collecting peripheral blood at the time point.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The dynamic changes of the number and type of CTCs and the correlation between DFS, OS and prognosis in breast cancer patients; | — |
Countries
China
Contacts
Public ContactRanli
Guizhou Cancer Hospital
Outcome results
None listed