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Expression of platelet derived growth factor family and its relationship with the onset and maintenance of non valvular atrial fibrillation and the TCM Syndrome Types

Expression of platelet derived growth factor family and its relationship with the onset and maintenance of non valvular atrial fibrillation and the TCM Syndrome Types

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-16009399
Enrollment
Unknown
Registered
2016-10-14
Start date
2016-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

auricular fibrillation

Interventions

Qi and yin deficiency:Clinical information and related examination results of patients
Type of heart Yang:Clinical information and related examination results of patients
Phlegm block type:Clinical information and related examination results of patients
Heart kidney yang deficiency:Clinical information and related examination results of patients
Heart vein blood stasis type:Clinical information and related examination results of patients

Sponsors

First Affiliated Hospital Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed as non valvular atrial fibrillation in hospital or outpatient department of Cardiology in our hospital. (Diagnostic criteria for atrial fibrillation: ECG or Holter showed P wave disappeared, replaced by absolute amplitude, shape, spacing of irregular "f" wave, and the HR is between 350-600 bpm, and the QRS waveform is in the room type, and the R-R interval is absolutely irregular.)

Exclusion criteria

Exclusion criteria: Over 80 years of age; with severe arrhythmia: including sick sinus syndrome, paroxysmal ventricular tachycardia, reverse ventricular tachycardia; severe heart failure, cardiac function grade 4, with a history of myocardial infarction in the past 3 months; with severe infection; the disorder of hypoxia and electrolyte is unable to correct; with other serious diseases of liver, kidney, hematopoietic system, endocrine system and so on; atrial fibrillation is secondary to heart valve disease.

Design outcomes

Primary

MeasureTime frame
platelet-derived growth factors, PDGF-AA;platelet-derived growth factors, PDGF-BB;platelet-derived growth factors, PDGF-DD;Vascular Endothelial Growth Factor, VEGF;Platelet derived growth factor receptor, PDGFRa;Platelet derived growth factor receptor, PDGFRß;Hypoxia inducible factor;Neuropeptide;Transforming growth factor;—

Countries

China

Contacts

Public ContactLiu Qiang

First Affiliated Hospital Zhejiang Chinese Medical University

13588121905@163.com+86 13588121905

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026