arterial stiffness
Conditions
Interventions
Hyperlipemia group:atorvastatin
control group:none
Pidotimod in Hyperlipemia group:Pidotimod and atorvastatin
Placebo in Hyperlipemia group:Placebo and atorvastatin
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Hyperlipidemia: under normal diet, total cholesterol (TC) is more than or equal to 5.72mmo/L or triglyceride (TG) is more than or equal to 1.7mmol/L or low density lipoprotein (LDL-C) is more than or equal to 3.64mmol/L or high density lipid protein cholesterol (HDL-C) is less than or equal to 0.91mmol/L,twice within 2 weeks, at least one factor match and except for other causes of dyslipidemia. Inclusion of normal group aim to be the reference of arterial stiffness and inflammatory factors level.
Exclusion criteria
Exclusion criteria: 1. physical scars, hypersensitive constitution and gut allergies; 2. pregnant or lactating women; 3. except for patients with secondary obesity dyslipidemia: pituitary tumor, hypothalamic syndrome, thyroid and gonadal function. Withdrawal syndrome, Cushing's syndrome, polycystic ovary syndrome, water retention, obesity, etc.; 4. Tuberculosis disease, severe diabetes, cancer, cardiovascular and cerebrovascular disease patients; 5. Patients with bleeding tendency; 6. Local skin infection or ulcer patients; 7. Coronary heart disease and other heart disease 8. According to different research purposes and research drug prescribed population. In addition 1) are participating in other clinical trials of patients; 2) researchers believe other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pulse wave velovity;CRP; | — |
Countries
China
Contacts
Public ContactBing Du
The first hospital of Jilin University
Outcome results
None listed