Fecundity evaluation of women of advanced age
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 35-45 years old; 2. Intent to achieve natural pregnancy in the following year; 3. Regular menstrual cycle; 4. Accept rugular follow-up; 5. Consent to the study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Irregular menstrual cycle; (2) Uterus malformation or uteral cavity adhesiion; (3) Edometriosis or teratoma, history of ovarian surgery; (4) Bilateral oviducts ligation or Bilateral oviducts obstruction revealed by HSG, and history of other oviduct surgery; (5) Autoimmune diseases, SLE et al.; (6) Thyroid disease; (7) History of malignant tumor or chemotherapy and radiotherapy; (8) Other major diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FSH;LH;Estradiol;Testosterone;Androstendione;SHBG;prolactin;TSH;total cholesterol;Triglyceride;LDL-C;HDL-C;AMH;VitB12;25(OH)D3;folate;AFC;semen analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| fasting glucose;Ht;Wt;WC;HC;BP; | — |
Countries
China
Contacts
Peking University Third Hospital