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The effect of sacral nerve stimulation (SNS) on symptom and neu-rohumoral regulation in patients with chronic constipation

The effect of sacral nerve stimulation (SNS) on symptom and neu-rohumoral regulation in patients with chronic constipation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-16008945
Enrollment
Unknown
Registered
2016-07-31
Start date
2016-08-30
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic functional constipation

Interventions

Treatment group:sacral nerve stimulation
Control group:Accept acupuncture Zhongliao acupoints (BL33) treatment.

Sponsors

Xijing Hospital of Degistive Diseases, Xijing Hospital, The Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients are diagnosed chronic constipation according to the Rome III criteria; 2. Patients could be considered including pelvic floor special examina-tion (Defecography, Slow transit constipation and Anorectal manome-try); 3. Patients also should accept this research treatment method.

Exclusion criteria

Exclusion criteria: 1. Does not meet the diagnostic criteria; 2. Could not sign the informed consent form; 3. Patients with Inflammatory bowel disease, Congenital malformation of anus and rectum, neurogenic disease (spinal injury, Multiple sclerosis, spina bifida, Parkinson's disease); 4. Patients who have symptoms according to significant psychological factors and uncontrolled hypertension, arrhythmia and diabetes.

Design outcomes

Primary

MeasureTime frame
the heart rate variability;cholecystokinin;nitric oxide synthase;the Cleveland Clinic Constipation Score;

Secondary

MeasureTime frame
Anorectal manometry;Slow transit constipation;

Countries

China

Contacts

Public ContactZheng Jianyong

Xijing Hospital of Degistive Diseases, Xijing Hospital, The Fourth Military Medical University

zhjy68@163.com+86 13891835899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026