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The mechanism of bidirectional regulation of acupuncture and moxibustion on Jak2-Stat3 pathway in cerebral ischemia reperfusion injury

The mechanism of bidirectional regulation of acupuncture and moxibustion on Jak2-Stat3 pathway in cerebral ischemia reperfusion injury

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-16008339
Enrollment
Unknown
Registered
2016-04-21
Start date
2016-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral ischemia reperfusion injury

Interventions

Acupuncture group:Acupuncture

Sponsors

The First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients with an age of more than 30 years of age less than 80 years of age and both sexes were eligible if they had an acute ischemic stroke a week ago; 2. The ischemic stroke was diagnosed according to the World Health Organization criteria for stroke and all patients had brain computed tomographic or magnetic resonance imaging scan to exclude intracerebral hemorrhage; 3. Only patients with limbs paralysis were included. The extent of paralysis had to be such that patients should be unable to walk or eat or dress without assistance; 4. informed consent; 5. completed the assessment before treatment.

Exclusion criteria

Exclusion criteria: 1. dependency in ADL before present stroke; 2. inability to complete scheduled treatment course; 3. infection in acupuncture sites; 4. severe aphasia or unconsciousness making it difficult to comprehend the study or cooperate in evaluation; 5. other severe complications or comorbidities such as heart/renal function failure.

Design outcomes

Primary

MeasureTime frame
the pathway of jak2-stat3;

Countries

China

Contacts

Public ContactWenxia Xie

The First Affiliated Hospital of Wenzhou Medical University

13868653068@163.com+86 13868653068

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026