Vascular Cognitive Impairment
Conditions
Interventions
Low-risk,Mediate-risk and High-risk:Cognitive Assesssment and MRI scan
Sponsors
Department of Neurology,Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. aged between 40 and 70,with at least one VRF; 2. no MR contradiction,including history of cardiac pacemaker implantation,in vivo metal implants, severe liver and kidney lung and cardiac insufficiency; 3. Cranial MRI showed key parts without vascular lesions, non-critical parts of vascular lesions > LCM vascular lesions 3 or less; 4. signed informed consent.
Exclusion criteria
Exclusion criteria: 1. a history of stroke and the positive sign of nervous system symptoms; 2. exclude other diseases of the central nervous system, such as brain tumors, intracranial infection, demyelinating disease and nervous system degenerative disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive score;VRFs burden;Volume of Hippocampus; | — |
Countries
China
Contacts
Public ContactDong Sun
Outcome results
None listed