chronic gastritis
Conditions
Interventions
PPI double dose group:none
PPIs standard dose group:none
Sponsors
Nanfang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18~70 years; 2. Inspection of Gastroendoscope and biopsy; 3. RUT (+) and UBT (+) confirmed the Hp infection and indication for Hp eradication; 4. Patients with Hp associated gastritis; 5. First time to received Hp eradication therapy; 6. Voluntary participation and sign a consent form.
Exclusion criteria
Exclusion criteria: 1. Previously received of hp eradication therapy; 2. The merger of GERD; 3. Allergic to esomeprazole, Amoxicillin and Clarithromycin; 4. Used of antibiotics, probiotics, bismuth, NSAIDs drugs in one month; 5. Used of the PPI, H2RA in two weeks; 6. Pregnant or lactating women; 7. Have a story of gastrointestinal operation; 8. Patients with pyloric obstruction; 9. A history of alcoholism or drug abuse history; 10. With servere heart, lung, liver kidney dysfunction and patients with malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 h pH monitor;CYP2C19;UBT; | — |
Countries
China
Contacts
Public ContactYe Chen
Outcome results
None listed