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Effect of intraoperative mean arterial pressure on periopertive renal injury and cognitive function in elderly patients with hypertension: a prospective, randomized cohort study

Effect of intraoperative mean arterial pressure on periopertive renal injury and cognitive function in elderly patients with hypertension: a prospective, randomized cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-15006892
Enrollment
Unknown
Registered
2015-08-07
Start date
2015-08-24
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension renal function

Interventions

three:mean arterial pressure

Sponsors

Shaoxing People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Elective surgical patients for gastrointestinal operation (for example, gastric cancer surgery, colorectral surgery); 2. Predicted duration of surgery>=60 min, aged 65-80 years; 3. Confirmed history of hypertension; 4. Non-nephrotic related surgery beyond 3 months; 5. Ejection fraction >50%.

Exclusion criteria

Exclusion criteria: 1. NSAIDs intake within latest 1 month; 2. Heart failure within 2 months; 3. Myocardial infarction within 1 month; 4. Severe pulmonary fuction insufficiency; 5. Intermediate to severe pulmonary hypertension; 6. Chronic kidney diseases or renal dysfunction.

Design outcomes

Primary

MeasureTime frame
Scr;CYS-C;NGAL;MMSE;—

Contacts

Public ContactZongming Jiang
jjiangzhejiang120@163.com+86 13515852725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026