Adult Congenital Heart Diseases with Intra-Cardiac Shunt
Conditions
Interventions
Control group:No intervention, Only monitoring
VSD group:No intervention, Only monitoring
ASD group:No intervention, Only monitoring
TOF group:No intervention, Only monitoring
SV group:No intervention, Only monitoring
Sponsors
Guangdong General Hospital, Guangdong Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Forty cases of adult patients with congenital heart diseases (with 10 cases of ventricular septal defect, atrial septal defect, tetralogy of Fallot or single ventricle in each group) to receive elective corrective surgeries. All genders, age 18~55 years old, BMI 20~24 kg/m2, ASA grade below III. All the patients are diagnosed as adult congenital heart diseases with intra-cardiac shunt by ultrasonography with normal lung, liver and kidney function. All the patients have no known hematological or neuromuscular conduction diseases, no medications affecting neuromuscular conduction taken before the surgeries and no histories of muscle relaxants allergy.
Exclusion criteria
Exclusion criteria: Patients with lung, liver or kidney dysfunction. Patients with neuromuscular conduction dysfunction. Patients taking medications affecting muscle relaxants before surgeries. Patients with known histories of anesthetic allergies. Patients with severe valvular stenosis or regurgitation. Patients or the family members refusing to participate the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma concentration of cis-atracurium;Onset time of cis-atracurium; | — |
Countries
China
Contacts
Public ContactSheng Wang
Outcome results
None listed