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Effects of the Cytochrome P450 Oxidoreductase Genetic Polymorphisms on Cytochrome P450 2B6 Activity in humans

Effects of the Cytochrome P450 Oxidoreductase Genetic Polymorphisms on Cytochrome P450 2B6 Activity in humans

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-15006690
Enrollment
Unknown
Registered
2015-06-17
Start date
2014-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nil

Interventions

bupropion group :bupropion

Sponsors

Department of Clinical Pharmacology, Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
24 Years to 34 Years

Inclusion criteria

Inclusion criteria: Chinese male healthy subjects without liver, kidney, heart, gastrointestinal, and nervous system and other chronic diseases.

Exclusion criteria

Exclusion criteria: Chinese people having a history of drug allergy, with liver, kidney, heart, gastrointestinal, and nervous system and other chronic diseases, take other drugs two weeks two weeks two weeks.

Design outcomes

Primary

MeasureTime frame
Cmax;plasma concentration;Tmax;inter-day precisions;intra-day precisions;genotype;

Countries

China

Contacts

Public ContactFan Lan
fanlan_038038@163.com+86-731-8480-5380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026