bronchial asthma
Conditions
Interventions
AG genetype :Inhaled corticosteroid treatment
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as asthmatic based on clinical symptoms and positive results of bronchial provocation or dilation tests according to the Global Initiative for Asthma (GINA) Guidelines; 2. Male or female aged 18 years or more; 3. Agreed to join the study and signed a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of active lung diseases other than asthma (chronic obstructive pulmonary disease, respiratory tract infections, bronchiectasis,etc); 2. Former smokers; 3. Recent (within 4 weeks) treatment with systemic or inhaled corticosteroids; 4. Allergic to inhaled corticosteroids orß2 agonists; 5. Serious conditions such as heart, liver, kidneys, lungs, gastrointestinal tract, endocrine or blood system diseases. History of alcoholism and drug abuse; 6. Current or recent (within 30 days) participation in another clinical study; 7. Other reasons that the researchers believed inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| genotype of GLCCI1 rs37973;Change in pulmonary function after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Concentrations of inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactJungang Xie
Outcome results
None listed