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Association study between the polymorphisms of KCNH2, RGS2, TRIB3 and the efficacy of antihypertensive drugs on essential hypertension therapy

Association study between the polymorphisms of KCNH2, RGS2, TRIB3 and the efficacy of antihypertensive drugs on essential hypertension therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RO-12002612
Enrollment
Unknown
Registered
2012-09-25
Start date
2007-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Essential Hypertension

Interventions

1:Nil

Sponsors

Institute of Clinical Pharmacology, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 85 Years

Inclusion criteria

Inclusion criteria: male or female patients, heart rates within 55 ~ 90 beats/min, systolic blood pressure (SBP) >=140 mmHg and /or diastolic blood pressure (DBP) >=90 mmHg were included.

Exclusion criteria

Exclusion criteria: Patients with secondary hypertension, coronary heart disease, diabetes, obesity (BMI>30kg/m2), stroke, renal or liver dysfunction, malignant tumor or pregnancy women and those whose blood pressure measurements above 180/110 mmHg or remaining lower than 140/90 mmHg during the wash-out period, were withdrawn from the study.

Design outcomes

Primary

MeasureTime frame
blood pressure;genotype;—

Countries

China

Contacts

Public ContactWei Zhang
yjsd2003@163.com+86 13973168774

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026