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To investigate the pathogenesis of intrauterine adhesion and the mechanism of amniotic mesenchymal stem cells in the treatment of intrauterine adhesion.

To investigate the pathogenesis of intrauterine adhesion and the mechanism of amniotic mesenchymal stem cells in the treatment of intrauterine adhesion.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RNC-17012799
Enrollment
Unknown
Registered
2017-09-26
Start date
2017-10-10
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrauterine adhesions

Interventions

normal group, adhesion group:without amniotic mesenchymal stem cells
normal group, model group, transplantation group 1, transplantation group 2:amniotic mesenchymal stem cells

Sponsors

University-Town Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Endometrium: (1) Meet the diagnostic criteria of intrauterine adhesions in the American reproductive association; (2) The serum sex hormone levels was in the normal range; (3) Did not receive any sex hormone therapy 3 months before the examination. 2. Placenta: Normal term selective cesarean section, no infectious disease, amniotic fluid, maternal voluntary to give up and donate the scientific research of abandoned placenta.

Exclusion criteria

Exclusion criteria: 1. Endometrium: Exclude endometriosis, uterine fibroids, habitual abortion, breast cancer, endometrial cancer, osteoporosis, thyroid disease, trigeminal neuralgia, certain medical diseases such as adrenal gland and other endocrine diseases, congenital disease; 2. Placenta: Exclude age less than 18 years old or above 40 years old, suffering from infectious diseases such as hepatitis B, hepatitis C, syphilis, AIDS, gonorrhea and other, suffering from severe maternal disease (such as intrahepatic cholestasis, fetal distress, placenta implantation).

Design outcomes

Primary

MeasureTime frame
functional gene;cell marker;

Countries

China

Contacts

Public ContactJia Wang

University-Town Hospital of Chongqing Medical University

752203031@qq.com+86 13508307321

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026