thoracic surgery
Conditions
Interventions
1:During OLV, FiO2 was increased to 100%. Seven steps were performed in the following sequence with each step lasting 4 minutes: 8 ml/kg, 12 breaths/min, 4 cmH2O (VT, fV and PEEP, respectively
same in the following steps)
8 ml/kg, 12 breaths/min, 0 cmH2O
6 ml/kg, 16 breaths/min, 8 cmH2O
6 ml/kg,&#
Sponsors
Shanghai Chest Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. patients scheduled for thoracic surgery; 2. need double lumen tube intubation and one lung ventilation; 3. Aged 18 to 70 years; 4. weight 40~80kg; 5. Baseline ASA score I or II.
Exclusion criteria
Exclusion criteria: 1. lung function is too low to bear single lung ventilation; 2. contraindication to double lumen tube intubation or difficult airway; 3. unstable hemodynamics preoperative; 4. pregnancy and lactation period; 5. any contraindication to the use of EIT (pacemaker, automatic implantable cardioverter defibrillator, and implantable pumps).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respiratory system compliance (Crs);PaO2,PaO2/FiO2;global inhomogeneity (GI) index; | — |
Countries
China
Contacts
Public ContactJingxiang Wu
Shanghai Chest Hospital, Shanghai Jiao Tong University
Outcome results
None listed