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Use of dynamic contrast-enhanced MRI to assess the blood brain barrier changes in patients with cognitive impairment associated with vascular risk factors

Use of dynamic contrast-enhanced MRI to assess the blood brain barrier changes in patients with cognitive impairment associated with vascular risk factors

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RNC-12002205
Enrollment
Unknown
Registered
2012-05-29
Start date
2012-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vascular cognitive impairment

Interventions

1:dynamic contrast-enhanced MRI

Sponsors

Neurologic department, Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 40 to 70 years old; 2. have at least one vascular risk factor according to Famingham stroke risk profile;3.Written informed consent was obtained from all patients.

Exclusion criteria

Exclusion criteria: 1. contraindications to MRI and stable condition to undergo an MRI exam; 2. have a history of stroke; 3. other CNS disease, such as tumor,infection,demyelinating diseases and neurodegenrative disease.

Design outcomes

Primary

MeasureTime frame
blood-brain barrier permeability;cognitive impairment;—

Countries

China

Contacts

Public ContactJunjian Zhang
xsssm@sina.cn+86 027 67813086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026