diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All subjects were evaluated through medical histories, physical examinations and routine clinical laboratory tests. T2DM was diagnosed in accordance with World Health Organization criteria in 1999 by fasting plasma glucose test (FPG) >=7.0 mmol/l and/or 2h postprandial plasma glucose test (PPG) >=11.1 mmol/l. The inclusion criteria were as follows: body mass index (BMI) between 19 and 30 kg/m2 and without administration of any insulin secretagogue, agonist and inhibitor of CYP2C8, CYP3A4 (such as rifampin, glitazones, gemfibrozil, antiviral drugs, anti-eumycete drugs, and glucoconicoids) in the past 3 months.
Exclusion criteria
Exclusion criteria: Subjects with type 1 diabetes mellitus, a history of ketoacidosis, ischemic heart disease, congestive heart failure, kidney, liver diseases or alcohol abuse, patients receiving insulin treatment or other drugs which affect glucose metabolism (such as glucocorticoids) and pregnant or lactating were excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood sugar; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood lipids; | — |