schizophrenia
Conditions
Sponsors
the Sixth Hospital, Peking University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: All subjects (male or female, 18-60 years old) are Chinese of Han descents and gave written informed consent for genetic study. The patients are recruited from the outpatient and inpatient departments of psychiatric hospitals. All patients fulfill the DSM-IV criteria for schizophrenia. The total scores of the PANSS are required above than 60 when the subjects are enrolled in the study.
Exclusion criteria
Exclusion criteria: The patients will be excluded when they: a) are diagnosed as the mental retardation, alcohol or drug addiction, according to the DSM-IV; b) suffer from the severe physical diseases, such as diabetes mellitus, thyroid gland disease, hypertension, other diseases as angel-closure glaucoma, epilapsy (febrile convulsion could be included); c) ever received the sustained-release antipsychotics, ECT or clozapine therapy one month ago; d) ever suffered from severe side effects related to antipsychotics, such as NMS, EPS, TD; e) with severe suicidal ideas or obvious excitation and agitation; f) with obvious abnormal index of laboratory examination; g) with poor therapeutic compliance or without custodians; h) with QTc interphase longer than 470 mses; i) female in pregnancy or lactation periods or planning to pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive and negative symptom scale (PANSS); | — |
Countries
China
Contacts
Public ContactYUE Weihua
Outcome results
None listed