meibomian gland dysfunction
Conditions
Interventions
Patients with meibomian gland dysfunction:Nil
Health vulunteers:Nil
Sponsors
Beijing Tongren Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged= 18 years old male and female; 2. After careful reading of the informed consent, the participants and project participants signed and dated the agreement; 3. Have one of the subjective symptoms, such as dry sense, foreign body sensation, burning sensation, fatigue feeling, discomfort and visual fluctuation ; 4. The slimp lamp inspection revealed the following changes: Blood congestion on the eyelid; Having irregular, thickened or obtuse lid margin; The formation of obstruction or lipids in the blepharopian glands; Gray line shift
Exclusion criteria
Exclusion criteria: 1. Eyelid and skin inflammatory , such as the anterior blepharitis, atopic dermatitis, seborrheic dermatitis and rosacea; 2. Eyelid and conjunctival scar disease, such as trachoma, blister, chemical injury, thermal burn, radiation injury, etc. 3. Eyelid abnormality (such as eyelid reversion, blepharopsis, tumor, edema, blepharospasm, eyelid closure, severe trichiasis, severe ptosis of the eyelid), the eyelid function of the eye; 4. Ocular surface abnomalies that may affect either the integrity of the cornea (for example, corneal chemical injury, recurrent corneal epithelium erosive, corneal epithelium defect and corneal fluorescein staining level 3, or map - dot - fingerprint malnutrition, etc.); 5. Systemic disease conditions lead to dry eyes, for example, Stevens - Johnson syndrome, vitamin A deficiency, rheumatoid arthritis, wegener granulomatosis, sarcoidosis, sarcoidosis, leukemia, systemic lupus erythematosus (sle), drying syndrome (Sjogren 's syndrome), etc.; 6. Unwilling or unable to stop using drugs known to cause dry eyes (such as iso-vitamin A acid and antihistamines). Subjects were not willing to stop the drugs at least one month before baseline examination; 7. The researchers determined that the subjects could not comply with the research requirements; 8. Pregnant women and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LLT;PB;Corneal perception;IR;Oxford Scheme;TBUT;Schirmer I without anesthetic;MGE; | — |
Countries
China
Contacts
Public ContactWang Ningli
Beijing Tongren Hospital, Capital Medical University
Outcome results
None listed