lupus erythematosus
Conditions
Interventions
Control group:methylprednisolone or other glucocorticoids
sTWEAK group:methylprednisolone or other glucocorticoids
Healthy control group:None
Sponsors
Department of Dermatology, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 75 years male or female; 2. Dignosed as lupus erythematosus; 3. who voluntarily participates in this trail and signs the informed consent.
Exclusion criteria
Exclusion criteria: (1) With overlapping connective tissue disease, mixed connective tissue disease or undifferentiated connective tissue disease; (2) Suffering from other autoimmune skin diseases and cutaneous vasculitis such as bullous pemphigoid, allergic purpura, Behcet's disease,et al; (3) With other inflammatory skin diseases, including psoriasis, eczema or atopic dermatitis,et al; (4) With other autoimmune diseases such as rheumatoid arthritis, inflammatory bowel disease (Crohn's disease and ulcerative colitis),et al; (5) Suffering from other systemic disease such as coronary atherosclerotic heart disease or diabetes; (6) Suffering from viral infectious skin diseases such as verruca vulgaris; (7) Under the period of severe local or systemic, acute or chronic infection; (8) With hepatitis B or C; or HIV antibody positivity; (9) With benign or malignant tumor; (10) Other conditions that researchers consider not appropriate to take part in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum sTWEAK;urine; | — |
Secondary
| Measure | Time frame |
|---|---|
| autoantibodies;complements;biochemical assay;erythrocyte sedimentation rate;blood routine;urine routine;C reactive protein; | — |
Countries
China
Contacts
Public ContactXia Yumin
Department of Dermatology, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University
Outcome results
None listed