Psoriasis
Conditions
Interventions
Case series:Nil
Sponsors
Institute of dermatology, Chinese Academyof Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Males and females aged between 16 and 75 years; 2. Patients who was diagnosed as generalized pustular psoriasis; 3. Provide written informed consent; 4. Willing and able to comply with all aspects of the protocol.
Exclusion criteria
Exclusion criteria: 1. Localized pustular psoriasis; 2. patients who has allergy of Tripterygium Glycosides and Acitretin any ingredient; 3. Patients who used any of the following systemic treatments within 4 weeks before the Baseline visit eg: corticosteroids, immuno-suppressive drugs, biologics; 4. History of hepatitis B or hepatitis C, and advanced HIV infection; 5. Laboratory data such as alanine aminotransferase (ALT), aspartate aminotransferase (AST) and blood lipid profile was 1.5 times higher than the normal limits; 6. Patients who has Active infectious disease or severe systemic disease currently; 7. Pregnant or lactating females or willing to pregnant in 2 years(involving male patients); 8. Any other situations not suitable for this study determined by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Glucose concentration;HbA1c;Blood Lipids concentration;Blood biochemical examination;Waist circumference;Hip circumference;Blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood-routine;Urine-routine test; | — |
Countries
China
Contacts
Public ContactBaoxi Wang
Institute of dermatology, Chinese Academyof Medical Sciences
Outcome results
None listed