Correlation study of valproic acid metabolism and UGT, CYP gene polymorphism

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-RCH-14005080

Enrollment

Unknown

Registered

2014-07-30

Start date

2014-08-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Interventions

1:gene normal

2:genetic mutations

Eligibility

Sex/Gender

All

Age

No minimum to 65 Years

Inclusion criteria

Inclusion criteria: 1. age 0-80 years old; 2. take the medicine at least one month; outpatients; take the medicine regularly; 3. the drug concentration is trough concentrations; 4. male and female; the han nationality patients; volunteer patients whose basic personal information is complete.

Exclusion criteria

Exclusion criteria: 1. patients whose basic personal information is uncompleted; 2. medication time is too short to the drug concentration did not reach steady state; 3. blood taking time does not meet the requirements, the patient does not agree; 4. patients who take the medicine not regularly.

Design outcomes

Primary

Measure	Time frame
Valproic acid concentrations;metabolites concentrations;liver function index;renal function index;blood routine inde;	—

Countries

China

Contacts

Public ContactHongying Ma

mhy808@tom.com+86 13723874141

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026