Association study between the polymorphism of CHRNA1 and the vecuronium-induce neuromuscular block

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-RCH-13003758

Enrollment

Unknown

Registered

2013-11-04

Start date

2013-11-11

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia

Interventions

The patients will be allocated by muscle relaxant:none

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Chinese patients of Han ethnicity; 2. Aged between 18 and 60 years; 3. female undergoing elective surgery under general anesthesiaASA I-II, BMI18.5-25Kg/m2; 4. The patients can fully understand the purpose of the study and possible adverse reactions to voluntarily participate in the experiment and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. BMI25kg/m2; 2. Diabetics; 3. hapatic,renal diseases; 4. acid-base imbalance or electrolyte disorder; 5. had neuromuscular diseases or was receiving any drugs know to affect the action of Neuromuscular blocking drugs6)Patient with difficult airway.

Design outcomes

Primary

Measure	Time frame
neuromuscular block;genotype;	—

Countries

China

Contacts

Public ContactHongwei Duan

Shanghai Pudong Hospital

duanhongwei120@126.com+86 18918790035

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026