Dental Caries, Candidiasis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Permanent dentine with the age between 13-25 years old; 2. The patients who need fixed orthodontic treatment in West China Hospital of Stomatology; 3. Willing to participate and sign the informed consent forms.
Exclusion criteria
Exclusion criteria: 1. active dental caries; 2. severe oral mucosa diseases; 3. using removable partial denture; 4. severe system diseases; 5. infectious diseases, inflammation, tumors; 6. antibiotic or hormone using within 1 month; 7. smokers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Streptococcus Mutants;Candida Albicans;Salivary SIgA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary flow rate;Salivary pH; | — |
Countries
China