The research of the correlation betweeen female sex hormones and propofol sedative effect

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-RCH-12002755

Enrollment

Unknown

Registered

2012-12-04

Start date

2012-10-08

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia sedation

Interventions

follicular group:the induction was implemented with propofol and remifentanyl infused via TCI pump

luteal groop:the induction was implemented with propofol and remifentanyl infused via TCI pump

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Adult female patients, aged 1840 years, ASA I-II, undergoing gynaecological laparoscopy were included in this study.-

Exclusion criteria

Exclusion criteria: Pregnancy, chronic or acute (within 48hr) intake any psychotropic drugs, any known adverse effect to the study drugs and severe hepatic, renal or neurological dysfunction,excessive alcohol drinkers, drug abusers and too thin (BMI33), women if they had premature ovarian failure (POF) or severely irregular menstrual cycles.

Design outcomes

Primary

Measure	Time frame
effect-site concentration of propofol at different time points;effect-site concentration of remifentanyl at different time points;The BIS-values at different time points;recovery times of anesthesia;the blood concentrations of female sex hormone;	—

Contacts

Public ContactChen Xinzhong

chenxinz@zju.edu.cn+86 13575738058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 22, 2026