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Prethrombotic State and Cardiac Events in Coronary Heart Disease Patients during Noncardiac Surgery

Prethrombotic State and Cardiac Events in Coronary Heart Disease Patients during Noncardiac Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RCH-12002685
Enrollment
Unknown
Registered
2012-11-17
Start date
2010-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Case series:Nil

Sponsors

Department of Anesthesiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
61 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included the following: age 61~75 years; elective abdominal surgery with moderate to high risk (general abdominal surgery, urinary surgery or gynecological surgery) and a surgery time of 90~180 min; CHD diagnosed according to the WHO criteria for CHD; stable angina or old myocardial infarction (6 months); cardiac function completely evaluated pre-operatively as New York Heart Association (NYHA) class I~II; prothrombin time, pre-surgery activated partial thromboplastin time, thrombin time, fibrinogen, and platelet count in the normal range; informed consent obtained before surgery

Exclusion criteria

Exclusion criteria: Exclusion criteria were the following: emergency surgery or low risk surgery; concomitant severe infection; dysfunction of liver, spleen, kidney or lung; malignancies; concomitant congenital heart disease, cardiomyopathy, rheumatic heart disease, pulmonary heart disease, severe heart failure or severe arrhythmia; unstable angina or myocardial infarction within the previous 3 months; hematological disease; intra-operative blood loss exceeding 20% of blood volume; inability (psychiatric disorders, consciousness disturbance, mental retardation) to cooperate with clinicians; and blood-borne infectious diseases (hepatitis B, hepatitis C, syphilis, AIDS).

Design outcomes

Primary

MeasureTime frame
D-dimer;thrombus precursor protein;thrombus precursor protein;

Countries

China

Contacts

Public ContactHong Zheng
hongz00@163.com+86 13565996995

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026