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Assosiation between Polymorphysim of the Opioid Receptor Gene and remifentanil analgesia and side effect

Assosiation between Polymorphysim of the Opioid Receptor Gene and remifentanil analgesia and side effect

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RCH-12002412
Enrollment
Unknown
Registered
2012-07-23
Start date
2012-02-20
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological diseases

Interventions

postoperation pain group:Flurbiprofen 100mg
nausea and vomiting group:Granisetron 3mg
Severe itching group:Dexamethasone 10mg
intraoperative pain group:Intravenous bolus of remifentanil 20ug each time, repeated an additional bolus after 2min

Sponsors

Department of Anesthesiology, Second Affiliated Hospital of Harbin Medical University, Heilongjiang Key Laboratory of Anesthesiology and Intensive Care Research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: females patients,aged between 18 and 55 yrs, Chinese Han origin, American Society of Anesthesiologists Physical Status I-II, body mass index 18-30kg/m2, who were scheduled to undergo hysterescopy surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: a history of psychiatric disease; cardiovascular, respiratory, hapatic, renal, endocrine, or immuce diseases; in addition, history of drug or alcohol abuse.

Design outcomes

Primary

MeasureTime frame
genetype;—

Countries

China

Contacts

Public ContactXi Hongjie
xihongjie1973@hotmail.com+86 13796652407

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026