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Liver transplantation for hepatocellular carcinoma in patients with cirrhosis:a cohort study comparison of the proposed Hangzhou criteria with the Milan criteria

Liver transplantation for hepatocellular carcinoma in patients with cirrhosis:a cohort study comparison of the proposed Hangzhou criteria with the Milan criteria

Status
Active, not recruiting
Phases
Phase 3
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-PRCH-10001077
Enrollment
Unknown
Registered
2010-09-24
Start date
2005-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Milan group:liver transplantation
Milan-Hangzhou group:liver transplantation
Beyond Hangzhou group:liver transplantation

Sponsors

Renji Hospital, Shanghai Jiaotong University School of Medicine,Shanghai Institute of Digestive Disease
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The diagnosis of hepatocellular carcinoma was confirmed in all patients either by computed tomographic scans or by serum alpha-fetoprotein measurement above 400 ng per milliliter and had histological prove after liver transplantation; 2. Histologically proved cirrhosis; 3. Had a history of hepatitis B virus infection, hepatitis B surface antigen positive or serum HBV-DNA positive or histologically proved HBV-relataed cirrhosis; 4. Underwent liver transplantation;

Exclusion criteria

Exclusion criteria: 1. Excluding the hepatocellular carcinoma patients with gross vascular invasion or metastatic disease; 2. Excluding the secondary liver transplantation and combined liver-kidney transplantation(LKT); 3. Excluding other malignant tumors in past history;

Design outcomes

Primary

MeasureTime frame
5-year recurrence probability;5-year survival rate;

Secondary

MeasureTime frame
5-year tumor-free survival probability;

Countries

China

Contacts

Public ContactHai Li
haili_17@126.com+86 13818525494

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026