Patients after craniotomy
Conditions
Interventions
Remifentenil group:Remifentenil bolus of 0.5ug/kg
Normal saline group:0.9% NS
Sponsors
Department of Critical Care Medicine, Beijing Tiantan Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with delayed extubation after craniotomy admitted to the ICU: 1. Aged 18-65 years old; 2. Consciousness and can cooperate to complete the visual analogue scale evaluation; 3. Comply with standard of extubion evaluated by neurosurgeon and ICU physician, and ready to be extubated.
Exclusion criteria
Exclusion criteria: Exclusion criteria are: 1. Operation related to medulla oblongata area; 2. Liver insufficiency; 3. Renal insufficiency; 4. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of patients with severe pain during extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS during extubation;Percentage of patients failed to pass extubation;Respiratory rate/heart rate/blood pressure/pulse, Blood oxygen saturation;Reintubation at 24 hours and 72 hours after Extubation;Percentage of patients with re-operation due to Intracranial hemorrhage or edema;Percentage of patients with severe side effect after giving medicine;Length of stay in ICU and hospital; | — |
Countries
China
Contacts
Public ContactJianxin Zhou
Department of Critical Care Medicine, Beijing Tiantan Hospital Affiliated to Capital Medical University
Outcome results
None listed