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Can butorphanol pretreatment reduce the frequency and severity of myoclonus induced by etomidate?

Can butorphanol pretreatment reduce the frequency and severity of myoclonus induced by etomidate?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-PRC-13003107
Enrollment
Unknown
Registered
2013-03-16
Start date
2013-03-16
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia

Interventions

Group B:Butorphanol pretreatment
Group S:Saline pretreatment

Sponsors

The Second Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA physical status I or II patients, aged 20-65 years old, undergoing general anesthesia for elective surgical procedures.

Exclusion criteria

Exclusion criteria: Patients with neurological disease, drug allergy, or those who had received analgesics, sedatives, or opioids within the previous 24 hours were excluded from the study.

Design outcomes

Primary

MeasureTime frame
The frequency and severity of myoclonus induced by etomidate, HR, R, BP;—

Countries

China

Contacts

Public ContactHe Liang
heliang72@yahoo.com.cn+86 13952057872

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026