hematologic malignancies
Conditions
Interventions
normal saline:mouthwash treatment with normal saline
Sodium bicarbonate solution:mouthwash treatment with 2.5% Sodium bicarbonate solution
1%nystatin solution:mouthwash treatment with 1% nystatin solution
Sponsors
Jiang Xiao-ying
Eligibility
Sex/Gender
All
Age
16 Years to 84 Years
Inclusion criteria
Inclusion criteria: Patients could be enrolled in the study if they did not receive hematopoietic stem cell transplantation but had hematologic malignancies including acute leukemia, chronic leukemia, lymphoma, multiple myeloma and myelodysplastic syndrome; they were hospitalized in the Department of Hematology of Affiliated Union Hospital of Fujian Medical University between 1 January 2010 and 31 December 2010; they were not transferred from another hospital or other departments of the Affiliated Union Hospital; they had no history of IPFI; and their expected hospital stay was longer than 9 days.
Exclusion criteria
Exclusion criteria: Patients were excluded from the study if they were diagnosed with IPFI within 48 h after admission [1]; their hospital stay was <=8 days; they were administered mouthwash for less than 8 days; they were also administered oral or venous anti-fungal agents to prevent fungal infections; or they were not compliant to the treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sputum fungal culture; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal fungal culture;Oral fungal culture; | — |
Countries
China
Contacts
Public ContactHu Rong
Outcome results
None listed