Mutiple interventions for prevention, early diagnosis and treatment of Esophageal squamous cell carcinoma: a large randomized control trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-PRC-09000452

Enrollment

Unknown

Registered

2009-06-28

Start date

2009-08-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early esophageal squamous cell carcinoma

Interventions

Enalapril group:Enalapril, 20mg, orally administrated twice daily

Aspirin group:Aspirin,100mg orally administrated once daily

Control group:Aspirin,100mg orally administrated once daily

Eligibility

Sex/Gender

All

Age

40 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Participants with high risk of esophageal cancer selected from screening of 4 high prevalence area of Handan, Hebei province; 2. Male and female aged in 40 to 65 years old.

Exclusion criteria

Exclusion criteria: 1. Contradiction to undergo gastroscopy; 2. Allergy to iodine; 3. Hyperthyroidism; 4. Advanced esophageal cancer; 5. Having other carcinoma; 6. Refusing to join in the research.

Design outcomes

Primary

Measure	Time frame
Parameters in endoscopic performance;Parameters of Patholog;	—

Countries

China

Contacts

Public ContactShutian Zhang

zhangst@ccmu.edu.cn+86 010 83168433

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026