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The role of myocardial scarring regions in the atrial fibrillation mechanism

Efficacy of modified matrix under high-density mapping to guide ablation of paroxysmal atrial fibrillation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-PPC-16008046
Enrollment
Unknown
Registered
2016-03-03
Start date
2016-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Interventions

B:Scar ablation
A:CPVA

Sponsors

First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 years and above; 2. At least one anti-arrhythmic drug therapy failed or could not tolerate; 3. preoperative antiarrhythmic drug withdrawal at least five half-life; 4. At least one of the following records are collected: ECG, Hollter etc; 5. There are indications of radiofrequency ablation; 6. able and willing to accept all preoperative, and postoperative follow-up examination.

Exclusion criteria

Exclusion criteria: 1. AF secondary to electrolyte imbalance, thyroid disease or other reversible or non-cardiac causes; 2. have received surgical ablation of atrial fibrillation or catheter ablation; 3. imaging results suggest left atrial thrombus; 4. decompensated heart failure, NYHA III-IV grade; 5. anticoagulation therapy contraindications; 6. serious organic disease: rheumatic heart disease, hypertrophic heart disease, dilated cardiomyopathy, coronary heart disease 7. received in the near future cardiac, abdominal and other difficult to tolerate surgery and short-term medical radiofrequency ablation; 8. with severe congenital disease or anomaly; 9. Life expectancy is not more than 365 days; 10. active systemic infection or sepsis; 11. A severe respiratory infection; 12. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Recurrence rate;

Countries

China

Contacts

Public ContactChang Dong

First Affiliated Hospital of Dalian Medical University

cdheart@126.com+86 18098875761

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026