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Dietary anthocyanins improve platelet function in subjects with dyslipidemia: a randomized clinical trial

Dose-response effects of dietary anthocyanins on platelet function in subjects with dyslipidemia: a randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-POR-17014242
Enrollment
Unknown
Registered
2017-12-31
Start date
2018-01-01
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

platelet function

Interventions

40mg / d anthocyanin intervention group:Oral anthocyanin capsules 40mg / day
80mg / d anthocyanin intervention group:Oral anthocyanin capsules 80mg / day
160mg / d anthocyanin intervention group:Oral anthocyanin capsules 160mg / day
320mg / d anthocyanin intervention group:Oral anthocyanin capsules 320mg / day

Sponsors

School of Public Health, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 35-65 years old, resident in Guangzhou City (living in Guangzhou for more than 10 years); 2. In line with China's prevention and treatment of dyslipidemia special subject group developed "dyslipidemia prevention and treatment recommendations" for the diagnosis of primary hyperlipidemia; 3. Meals of eating less out eating, weight stability in the past three months.

Exclusion criteria

Exclusion criteria: 1. Being suffering from diabetes; 2. Have had acute myocardial infarction, stroke, hypertension and other serious chronic diseases, cancer or liver and kidney dysfunction; had acute and chronic infectious diseases, trauma or surgery during the first half of the trial; is or has been hormone therapy patient; 3. Now taking or nearly six months have taken any hypolipidemic drugs, such as statins, fibrates, bile acid sequestrants, etc .; now or nearly 3 months taking vasomotor function and anti-inflammatory, antibiotics Drugs.2 months using any phytochemicals such as anthocyanins, grape seed extract and other dietary supplements; 4. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
platelet activation, aggregation and oxidative stress;

Secondary

MeasureTime frame
Inflammatory factor;Platelet granule release;Platelet chemokines;

Countries

China

Contacts

Public ContactYang yan

School of Public Health, SUN YAT-SEN UNIVERSITY

yangyan3@mail.sysu.edu.cn+86 020-87331597

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026