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Efficacy of high oxygen supply in perioperative period of thyroid surgery to prevent postoperative laryngopharyngeal symptoms, recurrent larygeal nerve palsy, and parathyroid dysfunction: a double blind randomized controlled trial

Efficacy of high oxygen supply in perioperative period of thyroid surgery to prevent postoperative laryngopharyngeal symptoms, recurrent larygeal nerve palsy, and parathyroid dysfunction: a double blind randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-POR-17012765
Enrollment
Unknown
Registered
2017-09-21
Start date
2017-12-01
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid disease

Interventions

A:High oxygen supply (FiO2 80%)
B:low oxygen supply (FiO2 80%)

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) more than 18 years of age; (2) diagnosis of thyroid disease requiring surgical treatment of cases; (3) ASA I-III; (4) general anesthesia; (5) volunteer to participate in this study, fill in the informed consent form, and agree to follow up.

Exclusion criteria

Exclusion criteria: (1) there was an emergency in the operation, which could not be given to oxygen in accordance with the requirements of high oxygen and hypoxia. (2) use of antiemetic or cough medicine 48 hours before surgery; (3) the patient has a history of depression, chronic pain history, islet dependent diabetes I or II, severe vomiting history; (4) pregnant women; (5) previous history of thyroid or cervical surgery; (6) cases of sternotomy for surgery are expected; (7) previous use of radiation iodine therapy; (8) preoperative sound has been altered or laryngoscope has been confirmed to have vocal cord paralysis; (9) merging other malignant tumors; (10) would not participate in this study.

Design outcomes

Primary

MeasureTime frame
Nausea, vomiting;cough;pain;Recurrent laryngeal nerve function;Parathyroid function;Inflammatory reaction;

Secondary

MeasureTime frame
Use of antiemetic;Use of cough medicine;bleeding;Use of analgesics;Postoperative hospitalization;Complications;

Countries

China

Contacts

Public ContactZhu Jingqiang

West China Hospital, Sichuan University

1263721733@qq.com+86 18980601477

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026