chronic obstructive pulmonary disease
Conditions
Interventions
1.COPD-OSAHS overlap:none
2.ACOS-OSAHS overlap:none
3.COPD:none
4.ACOS:none
Sponsors
Second Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria of COPD: 1. All subjects agreed to participate, understand the project, cooperate with relevant examinations,agree to follow-up, and signed informed consent; 2. Aged more than 40 years old, gender and ethnicity are not limited; 3. Conformed to the diagnostic criteria of Global Initiative for Chronic Obstructive Lung Disease; 4. Patients in stable stage. Inclusion criteria of ACOS(asthma-COPD overlap syndrome): Conformed to the diagnostic criteria of Diagnosis of Diseases of Chronic Airflow Limitation: Asthma, COPD and ACOS and more than 40 years old.
Exclusion criteria
Exclusion criteria: 1. Can not cooperate with related inspection or for other reasons; 2. Patients with interstitial pneumonia, active tuberculosis, community acquired pneumonia, lung cancer, bronchiectasis, pulmonary embolism; 3. History of drug abuse, alcohol abuse or anesthesia or with a history of mental illness (schizophrenia, obsessive-compulsive disorder, depression) and against personality, motivation, suspicious, or other emotional or mental issues that may affect participation in the study; 4. Taking part in other drug clinical trial project, or drop out less than 3 months; 5. During pregnancy, lactation women and illiteracy; 6. Heart disease (such as coronary heart disease, myocarditis, heart failure, neuromuscular disease, etc). And history of malignancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| COPD Assessment TestTM (CAT);Forced expiratory volume in one second (FEV1);St. George's Respiratory Questionnaire (SGRQ);Modified medical research council dyspnea scale;Berlin Questionnaire;The Epworth Sleeping Scale (ESS);Pittsburgh sleep quality index(PSQI);6 minutes walking test,6MWT;Pulmonary artery pressure;Atherosclerosis (AS) plaque;Apnoea–Hypopnoea Index (AHI); | — |
Countries
China
Contacts
Public ContactHuahao Shen
Second Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed