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Effect of alpha 2 adrenergic receptor agonist on gastrointestinal motility in patients after gastrectomy

Epidural dexmedetomidine improves the gastrointestinal motility function after radical gastrectomy in comparison with fentanyl

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-PNR-17011305
Enrollment
Unknown
Registered
2017-05-04
Start date
2017-05-06
Completion date
Unknown
Last updated
2017-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative gastrointestinal motility recovery

Interventions

Dexmedetomidine group:epidural administration of1.0 µg/kg dexmedetomidine 5 ml
Fentanyl Group:Epidural administration of 2µg/ml fentanyl 5ml

Sponsors

department of Anesthesiology ,Harbin Medical University Cancer Hospital,Ha Ping Road 150,Nan Gang Qu,Harbin,Hei Longjiang Province,China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 88 American Society of Anaesthesiology Physical Status I to III patients undergoing gastrectomy.

Exclusion criteria

Exclusion criteria: Patients were excluded if they met at least one of the following criteria: neurologic or psychiatric disease, known allergy to local anaesthetic, diabetes, a history of gastrointestinal motility disorders and epigastric operation, renal or hepatic insufficiency, bleeding or coagulation test abnormalities, were receiving anticoagulant, and emergency surgery.

Design outcomes

Primary

MeasureTime frame
first flatus (FFL);first feces (FFE);—

Countries

China

Contacts

Public ContactGuonian Wang

Harbin Medical University Cancer Hospital

wangguonian609cn@aliyun.com+86 13351880085

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026