non-small cell lung cancer
Conditions
Interventions
1: Stereotactic body radiotherapy
1:radiofrequency ablation
Sponsors
The Second Affiliated Hospital of Southeast University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) biopsy-proven NSCLC, including squamous cell carcinoma, adenocarcinoma, large cell neuroendocrine, and non-small cell carcinoma not otherwise specified; (2) Tumor within or touching the zone of the proximal bronchial tree defined as a volume of 2 cm in all directions around the proximal bronchial tree; (3) tumor size >3 cm but =5 cm, and staging studies must identify the lesion as T2aN0M0; (4) patient must be considered medically inoperable by an interdisciplinary group consisting of a pulmonologist, thoracic surgeon, medical oncologist, and radiation oncologist; (5) Karnofsky performance status (KPS) =70.
Exclusion criteria
Exclusion criteria: (1) tumor size >5 cm; (2) patients who have previously received radiation therapy to areas of the lung or mediastinum near target; (3) active systemic, pulmonary, or pericardial infection; (4) chemotherapy within 2 weeks of first planned fraction of SBRT; (5) pregnant women or women of childbearing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor local progression;Tumor metastasis rate; | — |
Countries
China
Contacts
Public ContactShilin Chen
Jiangsu Provincial Tumor Hospital
Outcome results
None listed