hypertension
Conditions
Interventions
Group A:taking the reference formulation first, then taking the test preparation
Group B:taking the test preparation first, then taking the reference formulation
Sponsors
The first affiliated hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
Male
Age
20 Years to 27 Years
Inclusion criteria
Inclusion criteria: (1) The healthy male; (2) Aged 18 ~ 40 years old, with a group of subjects no younger than 10 years of age; (3) The weight is higher than 50kg, body mass index (BMI) in the context of 19-25 kg/m2, [BMI= weight (kg)/height (m2)]; (4) Communicate well with the researchers and comply with the requirements of the entire study; (5) Fully understand the purpose, methods, and possible reactions of the trial, volunteered to participate in the trial and sign a informed consent form.
Exclusion criteria
Exclusion criteria: (1) Allergy somatoplasm, such as allergy to two or more drugs, foods and pollen; or known allergy to the components of the drug or Analogues; (2) Participated in other clinical trials within three months; (3) Donated blood within one month, or plan to donate blood during the trial or within 1 month at the end of the trial; (4) Used the test of reference drug within two week; (5) Volunteers who had a history of a cardiac, hepatic, renal, gastrointestinal, nervous system, psychiatric or metabolic abnormality; (6) The general examination and blood pressure, heart rate and respiratory conditions did not meet with standards; (7) Any significant clinical disease symptoms during physical examination revealed; (8) Laboratory tests (blood and urine routine, liver and kidney function, ECG and HIV et. al) found hematological abnormalities, heart, liver and kidney dysfunction; (9) Drug abusers, alcohol and smoke addiction; (10) Unsuitable to participate in the trial considered by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AUC0-t;Cmax; | — |
Contacts
Public ContactJianzhong Shen-tu
The first affiliated hospital, School of Medicine, Zhejiang University
Outcome results
None listed