Parkinson's Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All fulfilled the UK PDS Brain Bank criteria for prospective diagnosis of idiopathic Parkinsons disease, aged 30-85 years old and at modified Hoehn and Yahr stages 1–4.
Exclusion criteria
Exclusion criteria: 1. Atypical Parkinson syndrome; 2. A score of less than 24 on the mini-mental state examination; 3. Previous deep brain stimulation surgery; 4. Use of antipsychotic drugs; 5. Impaired renal function; 6. Liver function tests (ALT, AST) increased more than 2.5 times the upper limit of normal; 7. Severe infected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of HAMD;Score of PD-Q39; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total score of UPDRS II;Total score of UPDRS III;Score of HAMA;Score of PDSS;Score of BDI;Score of ADL; | — |
Countries
China
Contacts
Beijing Hospital