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Comparison of anti-diabetic medications during the treatment of atherosclerosis in T2DM patients

Comparison of anti-diabetic medications during the treatment of atherosclerosis in T2DM patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ORC-17010835
Enrollment
Unknown
Registered
2017-03-10
Start date
2015-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T2DM

Interventions

Case series:metformin, pioglitazone and sitagliptin

Sponsors

Anhui Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
42 Years to 70 Years

Inclusion criteria

Inclusion criteria: We enrolled 176 T2DM patients (160 male and 16 female) at Anhui Provincial Hospital Medical Center (Hefei, China) during the period of January 2015 and November. All of the enrolled T2DM patients met the WHO-1999 T2DM diagnostic criteria. The duration of diabetes was 1-5 years.

Exclusion criteria

Exclusion criteria: The following criteria were used for excluding patients: severe hepatic and kidney dysfunction; cardiac function grade 3-4; any systemic immune disorders; chronic inflammatory disease or tumor; severe diabetic complications; or an acute stress state within 2 months (surgical operation, active infection). Statin, ARB (angiotensin receptor blocker), and ACEI (angiotensin converting enzyme inhibitor) had not been taken.

Design outcomes

Primary

MeasureTime frame
Fasting Blood Glucose;Hemoglobin A1c (HbA1c);Triglycerides (TG);Total Cholesterol (TC);Low Density Lipoproteins (LDL);High Density Lipoproteins (HDL);Uric Acid (UA);Creatinine (Cr);CCA-IMT;recorded Systolic Pressure (SBD);height;weight;Serum IL-6;ADPN;

Countries

China

Contacts

Public ContactShandong Ye

Department of Endocrinology, Anhui Provincial Hospital

ysdcwsd@163.com+86 0551 62283526

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 27, 2026