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Comparison of Transoral Carbon dioxide Laser Microsurgery and Open Conservation Partial Laryngectomy in Early-Stage Laryngeal Carcinoma with Anterior Vocal Commissure Involvement

Comparison of Transoral Carbon dioxide Laser Microsurgery and Open Conservation Partial Laryngectomy in Early-Stage Laryngeal Carcinoma with Anterior Vocal Commissure Involvement

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ORC-17010515
Enrollment
Unknown
Registered
2017-01-24
Start date
2016-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laryngeal Carcinoma

Interventions

one:transoral laser microsurery group
two: partial laryngectomies

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 83 Years

Inclusion criteria

Inclusion criteria: Patients, from January 2006 to January 2016 in the First Affiliated Hospital of Zhongshan University, Department of Otolaryngology, diagnosed as early glottic cancer with anterior vocal commissure(AVC) involvement,underwent the surgery treatment(either transoral laser microsurery or partial laryngectomies)

Exclusion criteria

Exclusion criteria: 1. In addition to pathological for laryngeal squamous cell carcinoma (Such as adenocarcinoma, adenoid cystic carcinoma, papillary carcinoma etc.); 2. clinical stage Tis-2N0M0 cases outside, such as T3N0M0 or T4N0M0 cases; 3. tumor recurrence,lymph node metastasis or distant metastasis of the patients; 4. patients had received radiotherapy or oropharyngeal surgery; 5. patients with heart, brain, lung or other important organ dysfunction; 6. patients refused to participate in the study.

Design outcomes

Primary

MeasureTime frame
Survival Analysis;Questionnaire of QLQ-C30;Questionnaire of QLQ-H&N35;Vocie Handicap Index;Voice Analysis;GRABS;strobolaryngoscope;

Contacts

Public ContactWenbin Lei

Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University

leiwb@mail.sysu.edu.cn+86 13922113299

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026