Achalasia
Conditions
Interventions
A:Progressive full-thickness myotomy
B:Full-thickness myotomy in combination with indwelling anti-reflux belt
C:Circular muscle myotomy in combination with balloon shaping
Sponsors
Digestive Endoscopic Centre, Department of Gastroenterology and Hepatology. The Chinese PLA General Hospital.
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: Clinical diagnosed as achalasia by an physician with manometry diagnosis, barium esophagogram and endoscopic diagnosis.
Exclusion criteria
Exclusion criteria: 1. patients with severe achalasia(X-ray showed expansion and s-shaped tortuosity of the lower esophagus); 2. patients who had been treated by POEM and surgery; 3. Patients with severe coagulation disorders, severe organic diseases(such as heart, lung and kidney) who can not tolerate endoscopic operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower esophageal sphincter pressure;Symptom remission rate;Esophageal X-ray angiography (shape and width of esophagus);Endoscopic findings (esophagus residues, esophageal diameter, tightness degree of cardiac);Long-term complications (GERD); | — |
Secondary
| Measure | Time frame |
|---|---|
| The recurrence rate;Change of body weight; | — |
Countries
China
Contacts
Public ContactLing-hu Enqiang
Digestive Endoscopic Centre, Department of Gastroenterology and Hepatology.The Chinese PLA General Hospital.
Outcome results
None listed