The effect of preoperative PCA on the life quality and prognosis of orthopaedic fracture patients: a single center, randomised, and double blind clinical trial

The effect of preoperative Nalbuphine PCA on the life quality and prognosis of orthopaedic fracture patients: a single center, randomised, and double blind clinical trial

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OPh-17011866

Enrollment

Unknown

Registered

2017-07-04

Start date

2017-07-03

Completion date

Unknown

Last updated

2017-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute bone fracture

Interventions

Experimental group:Nalbuphine Preoperative continuous intraveous infusion analgesia

Control:Without Nalbuphine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification I-III, aged between 18-65 years, acute bone fracture patients; 2. Preoperative Visual analogue score>3; 3. Preoperative preparation time between 3-5days;

Exclusion criteria

Exclusion criteria: 1) with past diagnosis or treatment of psychological disease; 2) with severe anemia; 3) with hearing disorder; 4) with severe hypertention, or coronary heart disease, or diabetes mellitus,or COPD; 5) with autonomic immune diaseases; 6) without signing consent; 7) liver and renal function (ALT,ASTGLOBUN,Crea)>1.5fold of normal up-limit; 8) with difficulty in communication.

Design outcomes

Primary

Measure	Time frame
VAS;quality of sleep score;QOR-15;MMSE;	—

Secondary

Measure	Time frame
complications;	—

Countries

China

Contacts

Public ContactRuping Dai

The 2nd Xiangya Hospital, Central South University

909025585@qq.com+86 18974924753

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026