Recurrent Aphthous Stomatitis
Conditions
Interventions
test group: dried ginger film
control group:placebo
Sponsors
Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Having the ability to sign the informed consent form; 2. Aged 18~60 years old male and female; 3. Ulcer attack time is not more than 48 hours; 4. The frequency of attack is at least once every three months; 5. Pain discrimination; 6. According to the diagnostic criteria, clinical symptoms and signs of minor recurrent aphthous ulcer; 7. There were no more than 2 ulcers, and the ulcer diameter was not more than 5mm.;Inclusion criteria: 1. Having the ability to sign the informed consent form; 2. Aged 18~60 years old male and female; 3. Ulcer attack time is not more than 48 hours; 4. The frequency of attack is at least once every three months; 5. Pain discrimination; 6. According to the diagnostic criteria, clinical symptoms and signs of minor recurrent aphthous ulcer; 7. There were no more than 2 ulcers, and the ulcer diameter was not more than 5mm.;Inclusion criteria: 1. Having the ability to sign the informed consent form; 2. Aged 18~60 years old male and female; 3. Ulcer attack time is not more than 48 hours; 4. The frequency of attack is at least once every three months; 5. Pain discrimination; 6. According to the diagnostic criteria, clinical symptoms and signs of minor recurrent aphthous ulcer; 7. There were no more than 2 ulcers, and the ulcer diameter was not more than 5mm.;Inclusion criteria: 1. Having the ability to sign the informed consent form; 2. Aged 18~60 years old male and female; 3. Ulcer attack time is not more than 48 hours; 4. The frequency of attack is at least once every three months; 5. Pain discrimination; 6. According to the diagnostic criteria, clinical symptoms and signs of minor recurrent aphthous ulcer; 7. There were no more than 2 ulcers, and the ulcer diameter was not more than 5mm.;Inclusion criteria: 1. Having the ability to sign the informed consent form; 2. Aged 18~60 years old male and female; 3. Ulcer attack time is not more than 48 hours; 4. The frequency of attack is at least once every three months; 5. Pain discrimination; 6. According to the diagnostic criteria, clinical symptoms and signs of minor recurrent aphthous ulcer; 7. There were no more than 2 ulcers, and the ulcer diameter was not more than 5mm.
Exclusion criteria
Exclusion criteria: 1. Does not meet the above standards; 2. Severe recurrent aphthous stomatitis, Behcet's disease; 3. There are systemic diseases background: anemia, malignant tumor, peptic ulcer, Crohn's disease, acute infectious diseases, autoimmune diseases, etc.; 4. Other drugs have been used; 5. Lactating woman or pregnant woman; 6. Allergic to many kinds of drugs; 7. Participated in other drug clinical trials within 3 months; 8. Severe tooth wear.;Exclusion criteria: 1. Does not meet the above standards; 2. Severe recurrent aphthous stomatitis, Behcet's disease; 3. There are systemic diseases background: anemia, malignant tumor, peptic ulcer, Crohn's disease, acute infectious diseases, autoimmune diseases, etc.; 4. Other drugs have been used; 5. Lactating woman or pregnant woman; 6. Allergic to many kinds of drugs; 7. Participated in other drug clinical trials within 3 months; 8. Severe tooth wear.;Exclusion criteria: 1. Does not meet the above standards; 2. Severe recurrent aphthous stomatitis, Behcet's disease; 3. There are systemic diseases background: anemia, malignant tumor, peptic ulcer, Crohn's disease, acute infectious diseases, autoimmune diseases, etc.; 4. Other drugs have been used; 5. Lactating woman or pregnant woman; 6. Allergic to many kinds of drugs; 7. Participated in other drug clinical trials within 3 months; 8. Severe tooth wear.;Exclusion criteria: 1. Does not meet the above standards; 2. Severe recurrent aphthous stomatitis, Behcet's disease; 3. There are systemic diseases background: anemia, malignant tumor, peptic ulcer, Crohn's disease, acute infectious diseases, autoimmune diseases, etc.; 4. Other drugs have been used; 5. Lactating woman or pregnant woman; 6. Allergic to many kinds of drugs; 7. Participated in other drug clinical trials within 3 months; 8. Severe tooth wear.;Exclusion criteria: 1. Does not meet the above standards; 2. Severe recurrent aphthous stomatitis, Behcet's disease; 3. There are systemic diseases background: anemia, malignant tumor, peptic ulcer, Crohn's disease, acute infectious diseases, autoimmune diseases, etc.; 4. Other drugs have been used; 5. Lactating woman or pregnant woman; 6. Allergic to many kinds of drugs; 7. Participated in other drug clinical trials within 3 months; 8. Severe tooth wear.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| epidermal growth factor (EGF);tumor necrosis factor-a(TNF-a); | — |
Countries
China
Contacts
Public ContactYanling Fu;Yanling Fu;Yanling Fu;Yanling Fu;Yanling Fu ;;;;
Beijing University of Chinese Medicine;Beijing University of Chinese Medicine;Beijing University of Chinese Medicine;Beijing University of Chinese Medicine;Beijing University of Chinese Medicine
Outcome results
None listed