Skip to content

The efficacy and safety of Butorphanol for analgesia in ICU patients with mechanical ventilation:a multi-center clinical observation study

The efficacy and safety of Butorphanol for analgesia in ICU patients with mechanical ventilation:a multi-center clinical observation study

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OPN-17013368
Enrollment
Unknown
Registered
2017-11-13
Start date
2018-01-01
Completion date
Unknown
Last updated
2017-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical ventilation

Interventions

Case series:mechanical ventilation + butorphanol

Sponsors

The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Tracheal intubation and mechanical ventilation patients are expected to need at least 6h mechanical ventilation after entering the ICU; 2. Aged 18 years to 75 years male and female; 3. The patient or family members fully understand the purpose and significance of this experiment, and voluntarily participate in the clinical trial and sign the informed consent form.;Inclusion criteria: 1. Tracheal intubation and mechanical ventilation patients are expected to need at least 6h mechanical ventilation after entering the ICU; 2. Aged 18 years to 75 years male and female; 3. The patient or family members fully understand the purpose and significance of this experiment, and voluntarily participate in the clinical trial and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with brain damage and increased intracranial pressure; 2. bradycardia (heart rate or less 50 times/min), III degree atrioventricular block and other serious arrhythmia history; 3. Patients with acute myocardial infarction, ventricular dysfunction, and incomplete coronary artery dysfunction within 3 months; 4. Mental illness (such as schizophrenia, depression, etc.) and patients with cognitive dysfunction;Patients with a history of epilepsy;History of drug abuse and drug abuse; 5. Allergy to butorphanol or components; 6. Pregnant or lactating women; 7. The researchers judged that the patient was not suitable for other situations in which the clinical observation was made.;Exclusion criteria: 1. Patients with brain damage and increased intracranial pressure; 2. bradycardia (heart rate or less 50 times/min), III degree atrioventricular block and other serious arrhythmia history; 3. Patients with acute myocardial infarction, ventricular dysfunction, and incomplete coronary artery dysfunction within 3 months; 4. Mental illness (such as schizophrenia, depression, etc.) and patients with cognitive dysfunction;Patients with a history of epilepsy;History of drug abuse and drug abuse; 5. Allergy to butorphanol or components; 6. Pregnant or lactating women; 7. The researchers judged that the patient was not suitable for other situations in which the clinical observation was made.

Design outcomes

Primary

MeasureTime frame
Mechanical ventilation time;;Mechanical ventilation time;

Countries

China

Contacts

Public ContactLi Yu;Li Yu ;

The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology;The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology

yuli641006@sina.com;yuli641006@sina.com+86 13720168066;+86 13720168066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026