Dyslipidemia with atherosclerosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Any drugs that affect blood lipids have not been administrated during the one month before elected; (2) The test result of the blood sample, which is used to divide group, is the one collected within four weeks before taking berberine; (3) All the individuals selected are over 18 years of age (including 18 years) and under 80 years of age and not pregnant; (4) All the individuals in the group are informed consent and have signed the informed consent approved by the Ethics Committee.
Exclusion criteria
Exclusion criteria: 1. Patients are combined with liver and kidney dysfunction; 2, Patients could not follow the research program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood glucose, triglyceride, total cholesterol, low density lipoprotein;berberine and its metabolites;Amine and its derivatives;SCFA;Analysis of intestinal flora gene chip;Amino acids and its metabolites;neurotransmitter;nucleic acid metabolites;intestinal bacterial enzymes;Atherosclerotic plaque;brachial-ankle artery pulse wave velocity, baPWV; | — |
Countries
China
Contacts
The First Hospital of Jilin University