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The effect of berberine hydrochloride on the treatment of dyslipidemia with atherosclerosis

The effect of berberine hydrochloride on the treatment of dyslipidemia with atherosclerosis

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OPN-17012942
Enrollment
Unknown
Registered
2017-10-11
Start date
2017-06-05
Completion date
Unknown
Last updated
2017-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dyslipidemia with atherosclerosis

Interventions

Group 1:none
Group 2:Treated with berberine

Sponsors

The First Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Any drugs that affect blood lipids have not been administrated during the one month before elected; (2) The test result of the blood sample, which is used to divide group, is the one collected within four weeks before taking berberine; (3) All the individuals selected are over 18 years of age (including 18 years) and under 80 years of age and not pregnant; (4) All the individuals in the group are informed consent and have signed the informed consent approved by the Ethics Committee.

Exclusion criteria

Exclusion criteria: 1. Patients are combined with liver and kidney dysfunction; 2, Patients could not follow the research program.

Design outcomes

Primary

MeasureTime frame
Blood glucose, triglyceride, total cholesterol, low density lipoprotein;berberine and its metabolites;Amine and its derivatives;SCFA;Analysis of intestinal flora gene chip;Amino acids and its metabolites;neurotransmitter;nucleic acid metabolites;intestinal bacterial enzymes;Atherosclerotic plaque;brachial-ankle artery pulse wave velocity, baPWV;

Countries

China

Contacts

Public ContactQian Tong

The First Hospital of Jilin University

tongqian187@aliyun.com+86 13074337289

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026