focal segmental glomerulosclerosis
Conditions
Interventions
study group:prednisone treatment
Sponsors
Institute of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
17 Years to 80 Years
Inclusion criteria
Inclusion criteria: FSGS patients were recruited in the Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University from 2006 to 2016. The following qualifiers have to be fulfilled prior to the recruitment: (1) Aged between 17 and 80 years; (2) Renal biopsy was acquired; (3) EPI-eGFR=30 ml/min/1.73 m2; (4) 24-hour urine protein is between 1.0g-3.5g for equal to or more than twice; (5) Serum albumin>25g/L; (6) no remarkable decline in urine protein was observed after at least 1 month of ACEI/ARB drugs treatment; (7) no usage of glucocorticoids within 3 months prior to the study; (8) Signed informed consent.
Exclusion criteria
Exclusion criteria: Patients with the following features were excluded: (1) secondary FSGS; (2) family history of kidney diseases; (3) hepatitis virus carrier, chronic viral hepatitis or abnormal liver function; (4) any active or serious infection; (5) unwilling to adhere to the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h protein urine;serum albumin;creatinin; | — |
Countries
China
Contacts
Public ContactNan Chen
Nephrology Department, Ruijin Hospital, Shanghai Jiaotong university affiliated Ruijin Hospital
Outcome results
None listed